Cancer drugs

Modified on Fri, Mar 10, 2023 at 1:41 PM

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
Paclitaxel	Taxane	Breast cancer, lung cancer	Injection	Neutropenia, neuropathy, and myalgia	D
Cyclophosphamide	Alkylating Agent	Breast cancer and lymphoma	Oral, Injection	Neutropenia, alopecia, and cystitis	D
Doxorubicin	Anthracycline	Breast cancer and lymphoma	Injection	Cardiotoxicity, alopecia, nausea	D
5-Fluorouracil (5-FU)	Antimetabolite	Colorectal cancer, breast cancer	Injection, Topical	Myelosuppression, mucositis, and photosensitivity	D
Imatinib	Tyrosine kinase inhibitor	Chronic myeloid leukemia, gastrointestinal stromal tumor	Oral	Edema, fatigue, diarrhea	D
Rituximab	Monoclonal Antibody	Non-Hodgkin lymphoma, chronic lymphocytic leukemia	Injection	Infusion reactions, infections, hypotension	C
Tamoxifen	Selective Estrogen Receptor Modulator (SERM)	Breast cancer	Oral	Hot flashes, vaginal discharge, and thromboembolism	D
Cisplatin	Platinum-Based Chemotherapy	Testicular cancer, ovarian cancer	Injection	Nephrotoxicity, ototoxicity, and neuropathy	D
Methotrexate	Antimetabolite	Leukemia, lymphoma	Oral, Injection	myelosuppression, mucositis, liver toxicity	X
Trastuzumab	Monoclonal Antibody	Breast cancer, stomach cancer	Injection	Cardiotoxicity, infusion reactions, and diarrhea	D

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
Bevacizumab	Monoclonal Antibody	Colorectal cancer, lung cancer	Injection	Hypertension, bleeding, and gastrointestinal perforation	D
Erlotinib	Tyrosine kinase inhibitor	Lung cancer, pancreatic cancer	Oral	Rash, diarrhea, and nausea	D
Vinblastine	Vinca Alkaloid	Hodgkin lymphoma, non-Hodgkin lymphoma	Injection	Myelosuppression, neuropathy, constipation	D
Vincristine	Vinca Alkaloid	Hodgkin lymphoma, non-Hodgkin lymphoma	Injection	Myelosuppression, neuropathy, constipation	D
Etoposide	Topoisomerase Inhibitor	Lung cancer, testicular cancer	Oral, Injection	Myelosuppression, nausea, and hair loss	D
Carboplatin	Platinum-Based Chemotherapy	Lung cancer, ovarian cancer	Injection	Myelosuppression, nephrotoxicity, and neuropathy	D
Docetaxel	Taxane	Breast cancer, prostate cancer	Injection	Neutropenia, neuropathy, and myalgia	D
Doxil (doxorubicin hydrochloride liposome injection)	Anthracycline	Breast cancer, ovarian cancer	Injection	Cardiotoxicity, alopecia, nausea	D
Gemcitabine	Antimetabolite	Pancreatic cancer, lung cancer	Injection	myelosuppression, nausea, and rash	D
Bleomycin	Antibiotic	Hodgkin lymphoma, testicular cancer	Injection	Pulmonary toxicity, fever, and chills	D

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
Pembrolizumab	Immune Checkpoint Inhibitor	Melanoma, non-small cell lung cancer	Injection	Fatigue, cough, rash	D
Ipilimumab	Immune Checkpoint Inhibitor	Melanoma	Injection	Diarrhea, fatigue, and colitis	C
Atezolizumab	Immune Checkpoint Inhibitor	Bladder cancer, lung cancer	Injection	Fatigue, cough, rash	D
Brentuximab Vedotin	Antibody-Drug Conjugate	Hodgkin lymphoma, non-Hodgkin lymphoma	Injection	Peripheral neuropathy, fatigue, and nausea	D
Trametinib	Mitogen-Activated Protein Kinase (MAPK) Inhibitor	Melanoma, non-small cell lung cancer	Oral	Rash, diarrhea, and fatigue	D
Vemurafenib	BRAF Inhibitor	Melanoma	Oral	Rash, arthralgia, and fatigue	D
Nivolumab	Immune Checkpoint Inhibitor	Melanoma, non-small cell lung cancer	Injection	Fatigue, cough, rash	D
Dasatinib	Tyrosine kinase inhibitor	Leukemia	Oral	Myelosuppression, fluid retention, diarrhea	D
Temozolomide	Alkylating Agent	Brain tumors	Oral	Myelosuppression, nausea, fatigue	D
Cetuximab	Monoclonal Antibody	Colorectal cancer, head and neck cancer	Injection	Acneiform rash, hypomagnesemia, infusion reactions	C

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
L-asparaginase	Enzyme	Acute lymphoblastic leukemia	Injection	Hypersensitivity reactions, myelosuppression, and pancreatitis	C
Fludarabine	Antimetabolite	Chronic lymphocytic leukemia	Oral, Injection	Myelosuppression, fever, cough	D
Interferon alfa-2a	Interferon	Melanoma, chronic myeloid leukemia	Injection	Flu-like symptoms, depression, neutropenia	C
Methoxsalen	Psoralen	Cutaneous T-cell lymphoma	Oral	Nausea, dizziness, and skin photosensitivity	C
Mitoxantrone	Anthracenedione	Acute myeloid leukemia, prostate cancer	Injection	myelosuppression, cardiotoxicity, nausea	D
Oxaliplatin	Platinum-Based Chemotherapy	Colorectal cancer	Injection	Neuropathy, myelosuppression, and nausea	D
Palbociclib	Cyclin-Dependent Kinase (CDK) Inhibitor	Breast cancer	Oral	Neutropenia, fatigue, and nausea	D
Sorafenib	Tyrosine kinase inhibitor	Renal cell carcinoma, hepatocellular carcinoma	Oral	Hand-foot syndrome, diarrhea, and hypertension	D
Topotecan	Topoisomerase Inhibitor	Ovarian cancer, small cell lung cancer	Oral, Injection	myelosuppression, nausea, vomiting	D
Vincristine Sulfate Liposome Injection	Vinca Alkaloid	Acute lymphoblastic leukemia	Injection	Peripheral neuropathy, constipation, and nausea	D

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
Lenalidomide	Immunomodulatory Agent	Multiple myeloma	Oral	Fatigue, nausea, and myelosuppression	X
Abiraterone	androgen synthesis inhibitor	Prostate cancer	Oral	Hypertension, hypokalemia, fatigue	X
Daratumumab	Monoclonal Antibody	Multiple myeloma	Injection	Infusion reactions, myelosuppression, fatigue	D
Ibrutinib	Bruton's Tyrosine Kinase Inhibitor	Chronic lymphocytic leukemia, mantle cell lymphoma	Oral	Bleeding, diarrhea, and myelosuppression	D
Cabazitaxel	Taxane	Prostate cancer	Injection	Neutropenia, anemia, fatigue	D
Venetoclax	B-cell lymphoma 2 (BCL-2) inhibitor	Chronic lymphocytic leukemia	Oral	Neutropenia, diarrhea, and nausea	D
Osimertinib	Epidermal Growth Factor Receptor (EGFR) Inhibitor	Non-small cell lung cancer	Oral	diarrhea, rash, myelosuppression	D
Tisagenlecleucel	Chimeric antigen receptor (CAR) T-cell therapy	B-cell acute lymphoblastic leukemia	Intravenous Infusion	Cytokine release syndrome, neurological toxicity, infection	D
Pertuzumab	Monoclonal Antibody	Breast cancer	Injection	Diarrhea, nausea, and neutropenia	D
Romidepsin	Histone deacetylase (HDAC) inhibitor	Cutaneous T-cell lymphoma	Injection	Fatigue, nausea, and myelosuppression	D

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
Everolimus	mammalian target of rapamycin (mTOR) inhibitor	Breast cancer, pancreatic cancer	Oral	Fatigue, rash, and nausea	D
Alectinib	Anaplastic Lymphoma Kinase (ALK) Inhibitor	Non-small cell lung cancer	Oral	Edema, constipation, and myelosuppression	D
Sipuleucel-T	Autologous Cellular Immunotherapy	Prostate cancer	Intravenous Infusion	Infusion reactions, chills, fever	C
Pembrolizumab	Immune Checkpoint Inhibitor	Head and neck cancer, melanoma	Injection	Fatigue, cough, rash	D
Trastuzumab Emtansine	Antibody-Drug Conjugate	Breast cancer	Injection	Peripheral neuropathy, fatigue, and nausea	D
Enzalutamide	androgen receptor antagonist	Prostate cancer	Oral	Fatigue, hypertension, and myelosuppression	X
Brentuximab Vedotin	Monoclonal Antibody	Hodgkin lymphoma, non-Hodgkin lymphoma	Injection	Peripheral neuropathy, fatigue, and nausea	D
Mitomycin C	Antibiotic	Bladder cancer, gastric cancer	Injection	myelosuppression, nausea, vomiting	D
Necitumumab	Monoclonal Antibody	Non-small cell lung cancer	Injection	Rash, hypomagnesemia, and nausea	C
Olaparib	Poly(ADP-ribose) polymerase (PARP) inhibitor	Ovarian cancer	Oral	Myelosuppression, nausea, fatigue	D

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
Temozolomide	Alkylating Agent	Brain tumors	Oral	Myelosuppression, nausea, fatigue	D
Trametinib	Mitogen-Activated Protein Kinase (MAPK) Inhibitor	Melanoma, non-small cell lung cancer	Oral	Rash, diarrhea, and fatigue	D
Vemurafenib	BRAF Inhibitor	Melanoma	Oral	Rash, arthralgia, and fatigue	D
Nivolumab	Immune Checkpoint Inhibitor	Melanoma, non-small cell lung cancer	Injection	Fatigue, cough, rash	D
Dasatinib	Tyrosine kinase inhibitor	Leukemia	Oral	Myelosuppression, fluid retention, diarrhea	D
Carboplatin	Platinum-Based Chemotherapy	Lung cancer, ovarian cancer	Injection	Myelosuppression, nephrotoxicity, and neuropathy	D
Docetaxel	Taxane	Breast cancer, prostate cancer	Injection	Neutropenia, neuropathy, and myalgia	D
Doxil (doxorubicin hydrochloride liposome injection)	Anthracycline	Breast cancer, ovarian cancer	Injection	Cardiotoxicity, alopecia, nausea	D
Gemcitabine	Antimetabolite	Pancreatic cancer, lung cancer	Injection	myelosuppression, nausea, and rash	D
Bleomycin	Antibiotic	Hodgkin lymphoma, testicular cancer	Injection	Pulmonary toxicity, fever, and chills	D
Cisplatin	Platinum-Based Chemotherapy	Bladder cancer, testicular cancer	Injection	Nephrotoxicity, myelosuppression, and neuropathy	D

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
Rituximab	Monoclonal Antibody	Non-Hodgkin lymphoma, chronic lymphocytic leukemia	Injection	Infusion reactions, myelosuppression, fever	C
Ixabepilone	Epothilone	Breast cancer	Injection	Neuropathy, myelosuppression, fatigue	D
Idelalisib	Phosphoinositide 3-Kinase (PI3K) Inhibitor	Chronic lymphocytic leukemia	Oral	diarrhea, rash, liver toxicity	D
Folfirinox (5-FU, leucovorin, irinotecan, oxaliplatin)	Chemotherapy Combination	Pancreatic cancer	Intravenous Infusion	Myelosuppression, diarrhea, neuropathy	D
Cyclophosphamide	Alkylating Agent	Breast cancer, ovarian cancer	Oral, Injection	myelosuppression, nausea, vomiting	D
Cetuximab	Monoclonal Antibody	Colorectal cancer, head and neck cancer	Injection	Acneiform rash, hypomagnesemia, infusion reactions	C
Fluorouracil (5-FU)	Antimetabolite	Colorectal cancer, breast cancer	Injection, topical, or oral	Myelosuppression, nausea, mucositis	D
Goserelin	Gonadotropin-Releasing Hormone (GnRH) Agonist	Breast cancer, prostate cancer	Injection	Hot flashes, decreased libido, and bone loss	D
Lenograstim	Granulocyte Colony-Stimulating Factor (G-CSF)	Chemotherapy-Induced Neutropenia	Injection	Bone pain, fever, and headache	C
Mitoxantrone	Anthracenedione	Acute myeloid leukemia, prostate cancer	Injection	myelosuppression, cardiotoxicity, nausea	D

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
Ado-trastuzumab emtansine	Antibody-Drug Conjugate	Breast cancer	Injection	Fatigue, nausea, and peripheral neuropathy	D
Atezolizumab	Immune Checkpoint Inhibitor	Non-small cell lung cancer, bladder cancer	Injection	Fatigue, cough, and fever	D
Bortezomib	Proteasome Inhibitor	Multiple myeloma	Injection	Peripheral neuropathy, nausea, and diarrhea	D
Cabozantinib	Tyrosine kinase inhibitor	Kidney cancer, thyroid cancer	Oral	Diarrhea, fatigue, and hand-foot syndrome	D
Lenalidomide	Immunomodulatory Agent	Multiple myeloma	Oral	Fatigue, myelosuppression, diarrhea	X
Radium-223 dichloride	Radioactive Agent	Prostate cancer	Injection	Myelosuppression, nausea, and diarrhea	X
Regorafenib	Tyrosine kinase inhibitor	Colorectal cancer, gastrointestinal stromal tumor	Oral	Fatigue, hand-foot syndrome, hypertension	D
Venetoclax	B-cell lymphoma 2 (BCL-2) inhibitor	Chronic lymphocytic leukemia	Oral	Myelosuppression, nausea, and diarrhea	D
Zoledronic acid	Bisphosphonate	Bone metastases, multiple myeloma	Injection	Bone pain, fever, and flu-like symptoms	D
Temsirolimus	mammalian target of rapamycin (mTOR) inhibitor	Kidney cancer	Injection	Hyperglycemia, rash, fatigue	X

Please be aware that there are numerous additional cancer medications and treatments available, and this list is not all-inclusive. Additionally, because they are subject to change as new research becomes available, the categories for side effects and pregnancy listed here may not be current.