Warfarin

Increased risk of bleeding with other blood thinners or antiplatelet drugs

Bleeding, bruising, nausea, diarrhea

Metformin

Increased risk of low blood sugar with other drugs that lower blood sugar

Nausea, vomiting, diarrhea, abdominal discomfort

Albuterol

Increased risk of heart problems with other drugs that affect heart function

Headache, tremors, nervousness, throat irritation

Omeprazole

Reduced effectiveness of clopidogrel

Headache, nausea, diarrhea, abdominal pain

Gabapentin

Increased risk of side effects with other drugs that affect liver function

Drowsiness, dizziness, nausea, blurred vision

Ibuprofen

Increased risk of stomach bleeding with other blood thinners or corticosteroids

Nausea, heartburn, stomach pain, headache

Amoxicillin

Reduced effectiveness of hormonal contraceptives

Nausea, diarrhea, rash, yeast infections

Hydrochlorothiazide

Increased risk of low potassium levels with other drugs that lower potassium

Dizziness, headache, dry mouth, increased urination

Sertraline

Serotonin syndrome with other drugs that increase serotonin levels (e.g. MAOIs)

Nausea, diarrhea, insomnia, sexual dysfunction

Acetaminophen

Increased risk of liver damage with alcohol or other drugs that affect liver function

Nausea, vomiting, stomach pain, liver damage

Atorvastatin

Increased risk of muscle damage (rhabdomyolysis) with other drugs that affect liver function

Muscle pain, weakness, dark urine, liver damage

Citalopram

Serotonin syndrome with other drugs that increase serotonin levels (e.g. MAOIs)

Nausea, dry mouth, sexual dysfunction, dizziness

Losartan

Increased risk of low blood pressure with other blood pressure-lowering drugs

Dizziness, headache, fatigue, cough

Fentanyl

Increased risk of sedation and respiratory depression with other sedatives or antipsychotics

Drowsiness, nausea, constipation, respiratory depression

Levofloxacin

Increased risk of low blood sugar with other drugs that lower blood sugar

Nausea, diarrhea, headache, dizziness

Tramadol

Increased risk of sedation and respiratory depression with other sedatives or antipsychotics

Nausea, constipation, dizziness, headache

Aripiprazole

Increased risk of sedation and respiratory depression with other sedatives or opioids

Nausea, insomnia, agitation, dizziness

Lansoprazole

Reduced effectiveness of certain antibiotics and other medications that require stomach acid for absorption

Headache, nausea, diarrhea, abdominal pain

Pregabalin

Increased risk of side effects with other drugs that affect liver function

Dizziness, drowsiness, dry mouth, blurred vision

Trazodone

Increased risk of sedation and respiratory depression with other sedatives or opioids

Nausea, dizziness, drowsiness, headache

Digoxin

Increased risk of irregular heart rhythms with other drugs that affect heart function (e.g. amiodarone, quinidine)

Lithium

Increased risk of side effects with other drugs that affect kidney function (e.g. ACE inhibitors, diuretics)

Phenobarbital

Increased risk of sedation and respiratory depression with other sedatives or opioids

Methotrexate

Increased risk of side effects with other drugs that affect liver or kidney function (e.g. NSAIDs, diuretics)

Diltiazem

Increased risk of low blood pressure and heart problems with other blood pressure-lowering drugs

Carbamazepine

Increased risk of side effects with other drugs that affect liver function (e.g. rifampin, phenytoin)

Sotalol

Increased risk of irregular heart rhythms with other drugs that affect heart function (e.g. verapamil, amiodarone)

Clopidogrel

Increased risk of bleeding with other blood thinners or antiplatelet drugs

Levodopa

Reduced effectiveness with high-protein foods and other drugs that affect dopamine levels (e.g. antipsychotics, MAOIs)

Atenolol

Increased risk of low blood pressure and heart problems with other blood pressure-lowering drugs