Anti Seizure Medications

Modified on Wed, Feb 15, 2023 at 10:58 AM

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
Valproic acid	Fatty Acid Derivative	Epilepsy, bipolar disorder	Oral	Nausea, tremors, and weight gain	D
Lamotrigine	Sodium Channel Blocker	Epilepsy, bipolar disorder	Oral	Skin rash, headache, and dizziness	C
Topiramate	Sulfamate Substituted Monosaccharide	Epilepsy, migraine prophylaxis	Oral	Cognitive impairment, weight loss, and metabolic acidosis	D
Carbamazepine	Sodium Channel Blocker	Epilepsy, trigeminal neuralgia	Oral	Dizziness, diplopia, rash	D
Oxcarbazepine	Sodium Channel Blocker	Epilepsy, trigeminal neuralgia	Oral	Dizziness, somnolence, hyponatremia	C
Gabapentin	Gamma-Aminobutyric Acid (GABA) Analog	Epilepsy, neuropathic pain	Oral	Dizziness, somnolence, ataxia	C
Levetiracetam	Pyrrolidone Derivative	Epilepsy	Oral, Injection	Dizziness, somnolence, asthenia	C
Phenytoin	Sodium Channel Blocker	Epilepsy	Oral, Injection	Gingival hyperplasia, hirsutism, osteoporosis	D
Pregabalin	Gamma-Aminobutyric Acid (GABA) Analog	Epilepsy, neuropathic pain, and fibromyalgia	Oral	Dizziness, somnolence, and peripheral edema	C
Zonisamide	Sulfonamide Anticonvulsant	Epilepsy	Oral	Dizziness, somnolence, and anorexia	C

Drug Name	Drug Class	Indication	Route of Administration	Side Effects	Pregnancy Category
Felbamate	NMDA receptor antagonist	Epilepsy	Oral	Nausea, anorexia, and hepatotoxicity	X
Ezogabine	Potassium Channel Opener	Epilepsy	Oral	Urinary retention, dizziness, and confusion	C
Rufinamide	Sodium Channel Blocker	Epilepsy	Oral	Dizziness, somnolence, and nausea	C
Clobazam	Benzodiazepine	Epilepsy	Oral	Dizziness, sedation, and ataxia	D
Perampanel	AMPA receptor antagonist	Epilepsy	Oral	Dizziness, somnolence, and irritability	C
Brivaracetam	SV2A Ligand	Epilepsy	Oral	Dizziness, fatigue, somnolence	C
Cannabidiol	Cannabinoid	Epilepsy	Oral	Diarrhea, somnolence, and elevated liver enzymes	X
Fosphenytoin	Sodium Channel Blocker	Epilepsy	Injection	Phlebitis, cardiac arrhythmias, and hypotension	D
Lacosamide	Sodium Channel Blocker	Epilepsy	Oral, Injection	Dizziness, headache, nausea	C
Vigabatrin	GABA transaminase inhibitor	Epilepsy	Oral	Visual field defects, somnolence, weight gain	X

Please note that this list is not comprehensive and that there are many other seizure medications available for various indications. Additionally, the side effects and pregnancy categories listed here may not be up-to-date, as they are subject to change over time as new research becomes available. It's always important to consult with a healthcare professional before taking any medications.