Autoimmune Disorder	Symptoms	Testing Examples	Treatment
Rheumatoid Arthritis	Joint pain, stiffness, and swelling, fatigue, fever	Rheumatoid factor (RF), anti-cyclic citrullinated peptide (anti-CCP) antibody, erythrocyte sedimentation rate (ESR)	Nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs), biologic agents
Systemic Lupus Erythematosus	Joint pain, skin rashes, fever, fatigue, chest pain, shortness of breath	Antinuclear antibody (ANA), anti-dsDNA antibody, complement levels	Corticosteroids, antimalarials, immunosuppressants
Multiple Sclerosis	Fatigue, numbness or weakness in limbs, vision problems, trouble with coordination and balance	Magnetic resonance imaging (MRI), evoked potentials (EP)	Corticosteroids, disease-modifying therapies, physical therapy
Type 1 Diabetes	Increased thirst and urination, hunger, fatigue, blurred vision	Blood glucose test, A1C test, insulin autoantibodies	Insulin therapy, blood glucose monitoring, lifestyle changes
Celiac Disease	Abdominal pain, bloating, diarrhea, constipation, weight loss	Serologic tests for antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptides (DGP)	Gluten-free diet, nutritional supplements
Inflammatory Bowel Disease	Abdominal pain, diarrhea, bloody stools, weight loss, fatigue	Colonoscopy, biopsy, fecal calprotectin test	Anti-inflammatory drugs, immunosuppressants, biologic agents

 

 

Autoimmune Disorder	Symptoms	Testing Examples	Treatment
Hashimoto's Thyroiditis	Fatigue, weight gain, sensitivity to cold, dry skin, hair loss	Thyroid stimulating hormone (TSH), free thyroxine (T4), anti-thyroid peroxidase (anti-TPO) antibodies	Hormone replacement therapy
Psoriasis	Red, scaly patches on the skin, itching, nail changes	Physical exam, skin biopsy	Topical treatments, phototherapy, systemic medications
Sjögren's Syndrome	Dry eyes and mouth, joint pain, fatigue	Schirmer's test, salivary gland biopsy, anti-SSA and anti-SSB antibodies	Artificial tears, saliva substitutes, immunosuppressants
Myasthenia Gravis	Muscle weakness, fatigue, difficulty speaking or swallowing	Acetylcholine receptor (AChR) antibodies, repetitive nerve stimulation (RNS) test	Medications that enhance acetylcholine, immunosuppressants, thymectomy
Vitiligo	Loss of skin color in patches, hair color may also change	Physical exam, skin biopsy	Topical treatments, phototherapy, depigmentation therapy
Addison's Disease	Fatigue, muscle weakness, weight loss, low blood pressure, darkening of the skin	Blood tests for cortisol and adrenocorticotropic hormone (ACTH), ACTH stimulation test	Hormone replacement therapy

 

 

Autoimmune Disorder	Symptoms	Testing Examples	Treatment
Pemphigus Vulgaris	Blisters and sores on the skin and mucous membranes, pain in the mouth or throat	Skin biopsy, direct immunofluorescence (DIF) test	Corticosteroids, immunosuppressants, intravenous immunoglobulin (IVIG)
Polymyositis/Dermatomyositis	Muscle weakness and wasting, skin rash	Blood tests for muscle enzymes, electromyography (EMG), muscle biopsy	Corticosteroids, immunosuppressants, physical therapy
Guillain-Barré Syndrome	Muscle weakness and tingling sensations that start in the feet and hands and spread upwards	Nerve conduction studies, lumbar puncture	Intravenous immunoglobulin (IVIG), plasma exchange, supportive care
Goodpasture Syndrome	Lung and kidney damage, fatigue, shortness of breath	Blood tests for anti-glomerular basement membrane (GBM) antibodies, kidney biopsy	Immunosuppressants, plasmapheresis, dialysis
Ankylosing Spondylitis	Back pain and stiffness, joint pain, fatigue	Physical exam, blood tests for HLA-B27 antigen, X-rays or MRI	Nonsteroidal anti-inflammatory drugs (NSAIDs), biologic agents, physical therapy
Pernicious Anemia	Fatigue, weakness, shortness of breath, tingling or numbness in the hands and feet	Blood tests for vitamin B12 levels, intrinsic factor antibodies	Vitamin B12 injections, dietary changes

As always, please note that this is not an exhaustive list and that diagnosis and treatment can vary depending on the individual case. It is important to consult a healthcare professional if you have concerns about your health.